Chem Pharm.Bull. It also covers who shouldn't take it and what to look for when buying it. View abstract. View abstract. Immuno-stimulatory and hematopoietic activities of the leaf and seed aqueous extract of Phyllanthus Amarus in normal and cyclophosphamide-treated mice. Allison Herries, MS, RDN, CDN is a registered dietitian. View abstract. Chanca piedra may increase the excretion of electrolytes like potassium. An in vitro permeation of Phyllanthus amarus extract through human and shed snake skins. Ajala, T. O., Igwilo, C. I., Oreagba, I. Few clinical studies have been completed on chanca piedra. Nworu, C. S., Akah, P. A., Okoye, F. B., Proksch, P., and Esimone, C. O. Ahmeda, A., Hossain, M. A., and Zhari Ismail. Antibacterial activity of Phyllanthus amarus Schum and Thonn. J Nat Prod 1996;59:196-9. Wang XH, Li CQ Guo XB et al. 2007;64(6):547-552. Phytother.Res 2006;20(7):595-601. High-oxalate foods include beets, spinach, rhubarb, strawberries, nuts, chocolate, tea, wheat bran and beans (except lima and green beans). 1989;14(2):195-201. Phyllanthus amarus root clone with significant activity against bovine viral diarrhoea virus - a surrogate model of hepatitis C virus. View abstract. View abstract. Pharm.Biol. View abstract. 9 Remedies that Ease Vaccine Side Effects, Physically and Emotionally Exhausted? Studies have shown the potential for chanca piedra to help treat liver disorders, including hepatitis B, a viral liver infection. Why do animal sources of protein increase the risk of kidney stones? Stop using chanca piedra at least 2 weeks before a scheduled surgery. BJU Int. Folia Veterinaria 2005;49(2):65-69. Try to get more of your daily protein from vegetable sources. View abstract. 4-Methoxy-nor-Securinine, a New Alkaloid from Phyllanthus niruri. Innovative Food Science & Emerging Technologies 2010;526-532. Rai, V. and Mehrotra, S. Chromium-induced changes in ultramorphology and secondary metabolites of Phyllanthus amarus Schum & Thonn. J Gastroenterol Hepatol. View abstract. Nworu, C. S., Akah, P. A., Okoye, F. B., and Esimone, C. O. Aqueous extract of Phyllanthus niruri (Euphorbiaceae) enhances the phenotypic and functional maturation of bone marrow-derived dendritic cells and their antigen-presentation function. N.Z.Med J 6-22-1994;107(980):243. Current Science 2003;84(4):529-533. Gastroprotective and antioxidant activities of Phyllanthus amarus extracts on absolute ethanol-induced ulcer in albino rats. Indian J Gastroenterol. et. 11-1-2007;114(2):169-173. under water deficit conditions. It has been found that chanca piedra may help balance out uric acid and prevent gout attacks. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1999;12-31. Effects of oral administration of Phyllanthus amarus leaf extract on the kidneys of adult Wistar rats - a histological study. Journal of Experimental Zoology 2003;6(1):151-156. Oyewole IO, Moronkola DO Ogunwande IA et al. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. Investigation on the larvicidal activity of the plant Phyllanthus amarus against Anopheles stephensi. View abstract. When possible, choose a supplement tested by a trusted third party, such as USP, ConsurerLab, or NSF. For breastfeeding women, its best to avoid using the herb due to a lack of safety information. Chanca piedra may have interactions with herbal supplements exhibiting the same effects listed above, such as: It is essential to read the labels of supplements. vitamins, herbs, dietary supplements a-z list. Satyanarayana P, Subrahmanyam P Viswanatham KN et al. Campos, A. H. and Schor, N. Phyllanthus niruri inhibits calcium oxalate endocytosis by renal tubular cells: its role in urolithiasis. 1991;12(3):405-406. 2017 Jul; 9(7): 766. Urol.Res 2006;34(6):351-357. Lancet 6-30-1990;335(8705):1600-1601. International Journal of Phytomedicine 2011;115-119. Next to red peppers, you can get the most vitamin C from ________________. Indian J Exp Biol 1995; 33:861-4. Evaluation of the efficacy of Phyllanthus niruri standardized extract combined with magnesium and vitamin B6 for the treatment of patients with uncomplicated nephrolithiasis. Banerjee A, Chattopadhyay S. Effect of over-expression of Linum usitatissimum PINORESINOL LARICIRESINOL REDUCTASE (LuPLR) gene in transgenic Phyllanthus amarus. Med Pharm Rep. 2019 Apr; 92(2): 153157. J Pharm Pharmacol. Pramyothin, P., Ngamtin, C., Poungshompoo, S., and Chaichantipyuth, C. Hepatoprotective activity of Phyllanthus amarus Schum. Dhalwal, K., Biradar, Y. S., and Rajani, M. High-performance thin-layer chromatography densitometric method for simultaneous quantitation of phyllanthin, hypophyllanthin, gallic acid, and ellagic acid in Phyllanthus amarus. Yeh, S. F., Hong, C. Y., Huang, Y. L., Liu, T. Y., Choo, K. B., and Chou, C. K. Effect of an extract from Phyllanthus amarus on hepatitis B surface antigen gene expression in human hepatoma cells. Follow the package instructions for when to discard the supplement as well. Effect of extract of Phyllanthus niruri on crystal deposition in experimental urolithiasis. Warning letter: Herbs America, Inc, Boim MA, Heilberg IP, Schor N. Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. Zeitschrift fr Naturforschung 2006;57-60. Musuamba CT, Cimanga RK Dooghe L et al. Journal of Natural Remedies 2001;1(1):55-59. View abstract. Thonn. Treatment of chronic liver diseases with traditional Chinese medicine. Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. et Thonn. When taken with water pills, chanca piedra could cause your blood pressure to be too low.Lithium: Chanca piedra may act as a diuretic (water pill), impacting how efficiently the body gets rid of lithium. A prospective, randomised short term study [abstract no: 178] . Exploring alternative treatments for Helicobacter pylori infection. Indian J Biochem Biophys. Biology and Medicine 2009;28-33. View abstract. B. Etta H. Effects of Phyllanthus amarus on litter traits in albino rats. www.ars-grin.gov/duke (Accessed 3 November 1999). Hari Kumar, K. B. and Kuttan, R. Inhibition of drug metabolizing enzymes (cytochrome P450) in vitro as well as in vivo by Phyllanthus amarus SCHUM & THONN. Boca Raton, FL: CRC Press, LLC 1994. You are encouraged to report negative side effects of prescription drugs to the FDA. View abstract. 2005 - 2019 WebMD LLC. If youre prone to stones, following a few simple solutions can help: 1. Are Astragalus Supplements Right for You? 1996;39(3):211-215. Biol.Trace Elem.Res 2010;133(3):357-363. Patel HJ, Patel JS Patel KN. Pharm Biol. 2005;68(4):537-539. and Thonn.). Int Braz J Urol. 1990;32(4):212-218. Planta Med 1984;50(1):104-105. A. Molecular Medicine & Advance Sciences 2006;184-189. 2002 Jun;89(9):829-34. Pathophysiology. Pesticide Research Journal 2002;14(1):158-160. Bavarva JH, Narasimhacharya VR. View abstract. African Journal of Pharmacy and Pharmacology 2010;402-407. African Journal of Biotechnology 2010;3919-3922. Effect of Phyllanthus amarus on breeding efficiency of female albino rats. Vaccine 1990;8 Suppl:S86-S92. J Med Assoc.Thai. 2005;49(4):487-490. Water for preventing urinary stones. Dhooghe, L., Meert, H., Cimanga, R. K., Vlietinck, A. J., Pieters, L., and Apers, S. The quantification of ellagic acid in the crude extract of Phyllanthus amarus Schum. 2006;58(12):1559-1570. Modern studies show it also has powerful benefits in conditions ranging from ulcers to hepatitis B. View abstract. 2009;10(6):1089-1094. Rai, V., Khatoon, S., Bisht, S. S., and Mehrotra, S. Effect of cadmium on growth, ultramorphology of leaf and secondary metabolites of Phyllanthus amarus Schum. In about two-thirds of the participants, their kidney stones decreased in size and number. Thirunavukkarasu PS, Prathaban P Dhanapalan P. An experimental trial with Phyllanthus amarus in lantana toxicity of calves. Studies on the volatile oils of Momordica charantia L. (Cucurbitaceae) and Phyllanthus amarus Sch. In test-tube studies, chanca piedra extract has killed the bacterium Helicobacter pylori, which causes stomach ulcers. Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others. The Cochrane Library 2005;(1). View abstract. View abstract. LWT - Food Science and Technology 2007;1664-1669. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, COVID Robs Millions of Sense of Smell, Taste, U.S. Nears Top Spot in Global Monkeypox Cases, Diets Heavy in 'Ultra-Processed' Foods Could Harm the Brain, Some CBD Creams, Patches Don't Match Labels, Dr. Whyte's Book: Take Control of Your Diabetes Risk, Artificial Intelligence to Spot the Red Flags ofSuicide Risk, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. Sumathi, P Parvathi A. Antibacterial potential of Phyllanthus niruri L. Journal of Pure and Applied Microbiology 2011;425-428. The Healing Power of Plants: Medical Plants from Abuta and Acerola to Yohimbe and Yucca: a Practical Selection, MayaMedia Verlag, 2013. Amariin, a di-dehydrohexahydroxydiphenoyl hydrolysable tannin from Phyllanthus amarus. One of the earliest studies of chanca piedra found that people who drank a traditionally brewed tea for 1 to 3 months had a significantly reduced rate of kidney stones. 2010;32(3):393-401. Chanca piedra earned the name stonebreaker for its potential as a cure for kidney stones. Journal of Natural Products 1995;1515-1520. Sarkar, M. K. and Sil, P. C. Prevention of tertiary butyl hydroperoxide induced oxidative impairment and cell death by a novel antioxidant protein molecule isolated from the herb, Phyllanthus niruri. Vijayanand V, Nagarajan B Vasu K. Efficacy of Azadirachta indica and Phyllanthus amarus in experimental hepatitis in dogs. Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention. Fitoterapia 1993;64(3):235-238. Chanca piedra is also believed to impact the coagulation of platelets in the blood. View abstract. The right dose of any supplement depends on many factors, including age, body weight, and overall health. The pharmacological potential of Phyllanthus niruri. Joshi H, Parle M. Evaluation of the antiamnesic effects of Phyllanthus amarus in mice. A. and Akojenu, S. M. Anti-diarrhoeal and gastro-intestinal potentials of the aqueous extract of Phyllanthus amarus (Euphorbiaceae). Harikumar, K. B., Kuttan, G., and Kuttan, R. Inhibition of viral carcinogenesis by Phyllanthus amarus. Kerala Journal of Veterinary Science 1989;20(1):77-80. Taking too much chanca piedra has unknown effects. Other studies suggest it can also effectively treat hepatitis C virus and slow the progression of fatty liver disease. Lancet 10-29-1988;2(8618):1017-1018. View abstract. 2002;82(1):19-22. Bleeding disorder: Chanca piedra might slow blood clotting. Iizuka, T., Nagai, M., Taniguchi, A., Moriyama, H., and Hoshi, K. Inhibitory effects of methyl brevifolincarboxylate isolated from Phyllanthus niruri L. on platelet aggregation. Stay on the safe side and avoid use. McHarg T et al. Koday NK, Rangaiah GS Bobbrala V. In vitro control of some ocular infectious bacteria by using medicinal plants Adhatoda vasica, Cassia occidentalis and Phyllanthus amarus. Londhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Antioxidant activity of some polyphenol constituents of the medicinal plant Phyllanthus amarus Linn. Syamasundar, K. V., Singh, B., Thakur, R. S., Husain, A., Kiso, Y., and Hikino, H. Antihepatotoxic principles of Phyllanthus niruri herbs. We've updated our Privacy Policy, which will go in to effect on September 1, 2022. When taking antidiabetic medications, blood sugar levels may be too low. Asian Pac.J Cancer Prev. 2005;12(6-7):494-500. Nat.Prod.Res 2006;20(4):323-326. View abstract. View abstract. Read our. Try traditional herbs. Mehrotra, R., Rawat, S., Kulshreshtha, D. K., Goyal, P., Patnaik, G. K., and Dhawan, B. N. In vitro effect of Phyllanthus amarus on hepatitis B virus. View abstract. View abstract. For this reason, it's difficult for researchers to recommend one proper dosage to ensure safety and effectiveness. View abstract. 2003;87(2-3):193-197. 2000;73(1-2):215-219. Both these supplements have been shown to lower blood pressure. View abstract. Biol.Pharm.Bull. It Could Be Your Adrenals, Tame The Flames: 6 Anti-Inflammatory Supplements, Feeling Sluggish and Low on Energy? Journal of Applied Sciences and Environmental Management 2009;37-41. Study authors said that the chanca piedra might be effective against hepatitis B by slowing the replication (growth) of the hepatitis B virus. The National Institutes of Health notes that the Dietary Approaches to Stop Hypertension (DASH) diet can reduce the risk of kidney stones. B. These include: The FDA regulates supplementsas food, not as drugs. Advances in Plant Sciences 2009;433-436. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Kiemer, A. K., Hartung, T., Huber, C., and Vollmar, A. M. Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway. When eating oxalate-rich foods, eat or drink those rich in calcium. J-Clin-Epidemiol 1997;50(8S). Int Braz J Urol. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Dietary protein and potassium, dietdependent net acid load, and risk of incident kidney stones. Faremi, T. Y., Suru, S. M., Fafunso, M. A., and Obioha, U. E. Hepatoprotective potentials of Phyllanthusamarus against ethanol-induced oxidative stress in rats. Gastroprotective effect of Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. J Ethnopharmacol. 2010;48(1):396-401. 2011 Oct 1;21(19):5901-4. Hossain MA, Salehuddin SM. vitamins, herbs, dietary supplements a-z listchanca piedra. Monitor your blood sugar closely. A., and Odeku, O. J Ethnopharmacol. Chanca piedras antioxidant properties may improve liver function. Hussain RA, Dickey JK Rosser MP et al. Ranilla LG et al. Kumar, K. B. and Kuttan, R. Chemoprotective activity of an extract of Phyllanthus amarus against cyclophosphamide induced toxicity in mice. J Nat.Prod. Oluwafemi, F Debiri F. Antimicrobial effect of Phyllanthus amarus and Parquetina nigrescens on Salmonella typhi. View abstract. Journal of Pharmacy Research 2009;1869-1872. De Souza, T. P., Holzschuh, M. H., Lionco, M. I., Gonzalez, Ortega G., and Petrovick, P. R. Validation of a LC method for the analysis of phenolic compounds from aqueous extract of Phyllanthus niruri aerial parts. View abstract. Indian J Med Res 1982;76 Suppl:124-130. This article discusses what chanca piedra is used for and its possible side effects. In one older study, people with high blood pressure who took chanca piedra leaf powder showed a significant reduction in blood pressure, along with an increase in sodium excretion. J Pharm.Pharmacol. Obidike IC, Salawu OA Ndukuba M et al. The most common side effects of chanca piedra are: A clinical study of people with kidney stones noted these side effects. Sirajudeen KN, Sulaiman SA Madhavan M et al. There are few side effects of chanca piedra. Ambali SF, Adeniyi SA Makinde AO et al. A trial of Phyllanthus amarus in acute viral hepatitis [abstract]. View abstract. J Urol. J Med Virol. Shokunbi OS, Odetola AA. Effect of Phyllanthus amarus Schum. 2018;44(4):758-764. doi:10.1590/S1677-5538.IBJU.2017.0521, Ayala G, Escobedo-hinojosa WI, De la cruz-herrera CF, Romero I. View abstract. Find it in foods like potatoes, beet greens, avocados and spinach. 1993;40(1):53-58. Bankole HA, Magbagbeola OA Adu OB et al. What Are the Side Effects of Chanca Piedra? Effects of an aqueous extract from Phyllantus niruri on calcium oxalate crystallization in vitro. J Radiat.Res 2007;48(6):469-476. Dietary Approaches to Stop Hypertension (DASH) diet, Phyllanthus niruri: A Review on its Ethno Botanical, Phytochemical and Pharmacological Profile. AIDS Res Hum.Retroviruses 1992;8(11):1937-1944. and Thonn. Research Journal of Pharmaceutical Biological and Chemical Sciences 2010;335-340. J Ethnopharmacol. View abstract. Raintree tropical plant database, Amazon plants. Goldenroda classical exponent in the urological phytotherapy. Obasi BN, Igboechi CA Anuforo DC et al. Indian Journal of Virology 1997;13(1):59-64. Asian Journal of Experimental Sciences 2010; Bhattacharjee, R. and Sil, P. C. Protein Isolate from the Herb Phyllanthus niruri Modulates Carbon Tetrachloride-Induced Cytotoxicity in Hepatocytes. View abstract. and their pharmacological properties: a review. A novel class on non-peptidic endothelin antagonists isolated from the medicinal herb Phyllanthus niruri. At this time there is not enough scientific information to determine an appropriate range of doses for chanca piedra. www.ars-grin.gov/npgs (Accessed 3 November 1999). Duke JA, Vasquez R. Amazonian Ethnobotanical Dictionary. They alsoinspect supplement manufacturers. Harikumar, K. B. and Kuttan, R. An extract of Phyllanthus amarus protects mouse chromosomes and intestine from radiation induced damages. Munshi, A., Mehrotra, R., and Panda, S. K. Evaluation of Phyllanthus amarus and Phyllanthus maderaspatensis as agents for postexposure prophylaxis in neonatal duck hepatitis B virus infection. Increase insulin activity by Phyllanthus amarus Linn on liver cell regeneration in partially hepatectomised albino rats. Content is reviewed before publication and upon substantial updates. Active components of a Paraguayan crude drug "Para-parai mi," Phyllanthus niruri. J Chromatogr.A 6-22-2007;1154(1-2):198-204. 2005;68(1):129-132. This could impact heart rhythm. It is thought that chanca piedra contains chemicals that might relieve spasms and fever, increase urine, and have activity against bacteria and viruses. View abstract. 2008;147(1-3):307-315. National Institutes of Health. Paris: Lavoisier Publishing, 1995. Bhattacharyya R, Bhattacharya S Wenzel-Mathers M et al. View abstract. B reast f eeding. View abstract. Further research is needed to validate this effect. Narendranathan M, Mini PC Remla A. In a 2016 review, 50% to 60% of hepatitis B patients taking chanca piedra showed reduced hepatitis B antigen, a sign of infection. Bhattacharyya R, Bhattacharya S. Development of a potent in vitro source of Phyllanthus amarus roots with pronounced activity against surface antigen of the hepatitis B virus. View abstract. View abstract. Notka, F., Meier, G., and Wagner, R. Concerted inhibitory activities of Phyllanthus amarus on HIV replication in vitro and ex vivo. Clinical study of hepatoprotective drug Phyllanthus amarus. 2007;45(5):817-826. View abstract. Ishimoto H et al. Purification and characterisation of a novel antioxidant protein molecule from Phyllanthus niruri. 2. See additional information. Protective effectiveness of Phyllanthus niruri against short-term experimental aflatoxicosis in broiler chicken. View abstract.
7-15-2009;124(2):233-239. Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs. The effects of chromatographic fractions of Phyllanthus amarus Schum. Indian J Exp.Biol. One clinical study did note that chanca piedra was stored in a dry space at 59-95 degrees Fahrenheit. Although chanca piedra is an herb, it may pose some health risks. In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A. Bioorg Med Chem Lett. Khanna S, Srivastava, M. M., and Shalini Srivastava. McPartland JM. Food Chem Toxicol. Notka, F., Meier, G. R., and Wagner, R. Inhibition of wild-type human immunodeficiency virus and reverse transcriptase inhibitor-resistant variants by Phyllanthus amarus. Also known as stone breaker, chanca piedra has traditionally been used in Peru and the Amazonian rainforest to treat kidney stones and gallstones (hence its name). 2010 Jun;101(12):4676-89. The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation. Traditional Medicine and Nutraceuticals, A proceedings of WOCMAP III: The Third World Congress on Medicinal and Aromatic Plants 2003; Woottisin, S., Hossain, R. Z., Yachantha, C., Sriboonlue, P., Ogawa, Y., and Saito, S. Effects of Orthosiphon grandiflorus, Hibiscus sabdariffa and Phyllanthus amarus extracts on risk factors for urinary calcium oxalate stones in rats. Some studies suggest cranberry juice reduces kidney stone risk. Leelarasamee, A., Trakulsomboon, S., Maunwongyathi, P., Somanabandhu, A., Pidetcha, P., Matrakool, B., Lebnak, T., Ridthimat, W., and Chandanayingyong, D. Failure of Phyllanthus amarus to eradicate hepatitis B surface antigen from symptomless carriers. Clinical observation on 40 cases of chronic hepatitis B using compound Phyllanthus amarus combined with interferon. Please review the supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications. Adeneye, A. In a 2018 study, 56 people with kidney stones were given 4.5 grams of chanca piedra per day for 12 weeks. Umarani S. Larvicidal action of Phyllanthus niruri against the mosquito Culex quinquefasciatus. Lee, C. D., Ott, M., Thyagarajan, S. P., Shafritz, D. A., Burk, R. D., and Gupta, S. Phyllanthus amarus down-regulates hepatitis B virus mRNA transcription and replication. View abstract. However, more human studies are needed to determine the effects of chanca piedra on liver health. Urol.Res 2004;32(5):362-366. Eating, diet, and nutrition for kidney stones. Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. 7-23-2008;118(2):318-323. It is not recommended to take these supplements together as it may decrease your blood pressure to unsafe levels. Bao Y et al. Create a personalized feed and bookmark your favorites. Naik, A. D. and Juvekar, A. R. Effects of alkaloidal extract of Phyllanthus niruri on HIV replication. Exploring alternative treatments for Helicobacter pylori infection, Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri, Eating, diet, and nutrition for kidney stones, The kidney stone diet: Not as restricive as you may think, Infections (including sexually transmitted infections). 7. West African Journal of Pharmacology and Drug Research 2007;42-50. Latha, P., Chaitanya, D., and Rukkumani, R. Protective effect of Phyllanthus niruri on alcohol and heated sunflower oil induced hyperlipidemia in Wistar rats. Speak with a healthcare professional about taking chanca piedra if you are using diuretics or have any concerns about your potassium levels. Elfahmi, Batterman, S., Koulman, A., Hackl, T., Bos, R., Kayser, O., Woerdenbag, H. J., and Quax, W. J. Lignans from cell suspension cultures of Phyllanthus niruri, an Indonesian medicinal plant. Only a licensed healthcare provider should manage it. Integr.Cancer Ther. Planta Med 2006;72(14):1262-1267. Planta Med 2006;72(15):1353-1358. The herbal supplement nettle is believed to fight kidney stones as well. An improved HPLC method for estimation of phyllanthin and hypophyllanthin in Phyllanthus amarus. 4. Quality evaluation of Phyllanthus amarus (Schumach) leaves extract for its hypolipidemic activity. Peace Health. Viral hepatitis treated with Phyllanthus amarus and milk thistle (Silybum marianum): a case report [corrected]. View abstract. Acta Pol.Pharm. Diabetes: Chanca piedra might affect blood sugar levels. Talk to your healthcare provider before using it if you have any health conditions, including: Little is known about the effect of chanca piedra on pregnancy, children, and people over 65. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use chanca piedra. Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats. In vitro study on alpha-amylase inhibitory activity of an Indian medicinal plant, Phyllanthus amarus. Dosage: How Much Chanca Piedra Should I Take? View abstract. View abstract. Bhattacharjee, R. and Sil, P. C. Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties. Some "water pills" include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others. Abhyankar G, Suprasanna P Pandey BN et al. Murali B, Amit A Anand MS et al. on five vegetative organisms. Sundaresan NR, Thirumurugan R Jayakumar S et al. Bagalkotkar, G., Sagineedu, S. R., Saad, M. S., and Stanslas, J. Phytochemicals from Phyllanthus niruri Linn. J Pharm Pharmacol. Therapeutic observation of Phyllanthus amarus for treatment of hepatitis B . Phyllanthus. The herb is believed to have health benefits in treating ulcers, urinary tract stones, and various conditions related to the kidneys, liver, and digestive system.. J Urol. There are various diets for the prevention of different types of kidney stones. While this effect can help manage hyperglycemia (high blood sugar) in animals, more human studies are needed. Mellinger, C. G., Cipriani, T. R., Noleto, G. R., Carbonero, E. R., Oliveira, M. B., Gorin, P. A., and Iacomini, M. Chemical and immunological modifications of an arabinogalactan present in tea preparations of Phyllanthus niruri after treatment with gastric fluid.
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